2020 Philippines Football League champions United City FC and 2021 Copa Paulino Alcantara winners Kaya FC-Iloilo will once again represent the country in the international stage having been nominated to compete in AFC Club Competitions for 2022.

Both PFL clubs learned their fate following the AFC Champions League 2022 and AFC Cup 2022 group stage draws held Monday, 17 January 2022 in Kuala Lumpur, Malaysia..

United City were drawn against BG Pathum United of Thailand, Jeonnam Dragons of Korea Republic, and Melbourne City FC of Australia in Group G. While Kaya FC-Iloilo will have to go through the preliminary and play-off round against the third placed team from Australia and the Changchun Yatai of China PR.

2021 Copa Paulino Alcantara winners Kaya FC-Iloilo meanwhile, have one foot to the Champions League through the preliminary and play-off stages. Kaya will face the third placed team from Australia on 08 March 2022 with the winner facing Changchun Yatai of China PR in the play-off round on 15 March 2022.

Kaya will be in Group H alongside Jeonbuk Hyundai Motors of Korea Republic, Yokohama F. Marinos of Japan, and Hoang Ahn Gia Lai of Vietnam should they win their matches in the preliminary and play-off rounds.

If Kaya fails to qualify for the Champions League, they will compete in the AFC Cup 2022 ASEAN Zone where they will face Bali United of Indonesia, Keda Darul Aman FC of Malaysia, and the Play-off round between the teams of Cambodia and Laos..